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American Journal of Neuroradiology, Vol 11, Issue 5 983-986, Copyright © 1990 by American Society of Neuroradiology

ARTICLES

Meningeal dissemination of retinoblastoma: CT findings in eight patients

FJ Meli, CA Boccaleri, J Manzitti and P Lylyk
Department of Neuroimaging, Raul Carrea Institute for Neurological Research, Buenos Aires, Argentina.

Thirty-seven patients with retinoblastoma were evaluated prospectively by clinical examination, lumbar puncture, and CT. Eight (22%) of the 37 were found to have meningeal dissemination. The tumor was bilateral in three patients. Two cases showed no CT signs of local recurrence. Headache, nausea/vomiting, and restlessness were the most common symptoms. CT scans in these patients showed diffuse meningeal contrast enhancement, nodular masses, ependymal-subependymal enhancement, and ventricular dilatation. Our series of eight patients with meningeal spread illustrates a considerable range of dissemination patterns referable to retinoblastoma. One case illustrated the CT finding of multiple epidural metastases.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X