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American Journal of Neuroradiology, Vol 12, Issue 1 83-85, Copyright © 1991 by American Society of Neuroradiology


ARTICLES

Xenon-enhanced CT of the brain: effect of flow activation on derived cerebral blood flow measurements

WF Good and D Gur
Department of Diagnostic Radiology, University of Pittsburgh, PA 15261.

The errors associated with derivation of cerebral blood flow values by the xenon-enhanced CT method have been evaluated through computer simulations as a function of flow-activation patterns and different scanning protocols. The results of this study indicate that actual flow activation during inhalation increases the derived flow values in a systematic way. Compared with the errors introduced by CT noise and/or variations in scanning protocols, flow activation introduces relatively small errors in the derived flow value when the washin technique is used.


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