American Journal of Neuroradiology, Vol 17, Issue 5 979-985, Copyright © 1996 by American Society of Neuroradiology
ARTICLES |
Cerebral visual impairment in periventricular leukomalacia: MR correlation
C Uggetti, MG Egitto, E Fazzi, PE Bianchi, R Bergamaschi, F Zappoli, L Sibilla, A Martelli and G Lanzi
Servizio di Neuroradiologia, IRCCS Instituto Neurologico Fondazione C. Mondino, Pavia, Italia.
PURPOSE: To evaluate the involvement of central visual pathways in cases of periventricular leukomalacia, and to correlate the neuroradiologic findings with the degree of visual acuity. METHODS: The MR brain examinations of 27 preterm children affected by cerebral palsy resulting from periventricular leukomalacia and without significant ophthalmologic lesions were reviewed retrospectively to search for possible involvement of the optic radiations and/or of the calcarine cortex. The data were compared with the degree of visual acuity estimated by means of the Teller Acuity Cards test. RESULTS: Seventeen (63%) of the 27 patients had cerebral visual impairment, which correlated strongly with MR lesions. Quantitative reduction and signal hyperintensity of the peritrigonal white matter and atrophy of the calcarine cortex were present in the more severe cases. In two blind patients, an altered MR signal was detected in the lateral geniculate bodies. CONCLUSION: This study clearly establishes a relationship between specific MR findings and visual impairment in children with periventricular leukomalacia. The finding of hyperintensity in the lateral geniculate bodies was interpreted as an axonal reaction. MR imaging is useful for detecting potential visual impairment and for improving clinical diagnosis.
This article has been cited by other articles:
 |
|
 |
|
  F. Ghasia, J. Brunstrom, M. Gordon, and L. Tychsen Frequency and Severity of Visual Sensory and Motor Deficits in Children with Cerebral Palsy: Gross Motor Function Classification Scale Invest. Ophthalmol. Vis. Sci., February 1, 2008; 49(2): 572 - 580. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Bassi, D. Ricci, A. Volzone, J. M. Allsop, L. Srinivasan, A. Pai, C. Ribes, L. A. Ramenghi, E. Mercuri, F. Mosca, et al. Probabilistic diffusion tractography of the optic radiations and visual function in preterm infants at term equivalent age Brain, February 1, 2008; 131(2): 573 - 582. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Tychsen, M. Richards, A. M. F. Wong, J. Demer, D. Bradley, A. Burkhalter, and P. Foeller Decorrelation of Cerebral Visual Inputs as the Sufficient Cause of Infantile Esotropia Amer. Orthoptic Jrnl., January 1, 2008; 58(1): 60 - 69. [Abstract] [PDF]
|
|
|
|
 |
|
 E. Fazzi, S. G. Signorini, S. M. Bova, R. La Piana, P. Ondei, C. Bertone, W. Misefari, and P. E. Bianchi Spectrum of Visual Disorders in Children With Cerebral Visual Impairment J Child Neurol, March 1, 2007; 22(3): 294 - 301. [Abstract] [PDF]
|
|
|
|
|
|
D. K. Shah, C. Guinane, P. August, N. C. Austin, L. J. Woodward, D. K. Thompson, S. K. Warfield, R. Clemett, and T. E. Inder Reduced Occipital Regional Volumes at Term Predict Impaired Visual Function in Early Childhood in Very Low Birth Weight Infants. Invest. Ophthalmol. Vis. Sci., August 1, 2006; 47(8): 3366 - 3373. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R S Lowery, D Atkinson, and S R Lambert Cryptic cerebral visual impairment in children Br. J. Ophthalmol., August 1, 2006; 90(8): 960 - 963. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. K. Larsson, A. C. Rydberg, and G. E. Holmstrom A Population-Based Study on the Visual Outcome in 10-Year-Old Preterm and Full-Term Children Arch Ophthalmol, June 1, 2005; 123(6): 825 - 832. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Fujita, H. Tanaka, M. Takanashi, N. Hirabuki, K. Abe, H. Yoshimura, and H. Nakamura Lateral Geniculate Nucleus: Anatomic and Functional Identification by Use of MR Imaging AJNR Am. J. Neuroradiol., October 1, 2001; 22(9): 1719 - 1726. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Brodsky Periventricular Leukomalacia: An Intracranial Cause of Pseudoglaucomatous Cupping Arch Ophthalmol, April 1, 2001; 119(4): 626 - 627. [Full Text] [PDF]
|
|
|
|
 |
|
 G. Cioni, B. Bertuccelli, A. Boldrini, R. Canapicchi, B. Fazzi, A. Guzzetta, and E. Mercuri Correlation between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia Arch. Dis. Child. Fetal Neonatal Ed., March 1, 2000; 82(2): 134F - 140. [Abstract] [Full Text]
|
|