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American Journal of Neuroradiology, Vol 17, Issue 7 1290-1294, Copyright © 1996 by American Society of Neuroradiology


ARTICLES

Reversible leukoencephalopathy associated with graft-versus-host disease: MR findings

JM Provenzale and ML Graham
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.

Ten weeks after undergoing bone marrow transplantation for metastatic lymphoma of the parotid gland, a 9-year-old girl became disoriented and had tremor and myoclonus in the context of graft-versus-host disease (GVHD). MR images showed abnormal signal primarily within the brain stem and deep white matter, which resolved almost completely after treatment. The findings are consistent with brain involvement by GVHD.


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