American Journal of Neuroradiology, Vol 17, Issue 8 1589-1591, Copyright © 1996 by American Society of Neuroradiology
ARTICLES |
Whipple disease confined to the central nervous system in childhood
TP Duprez, CB Grandin, C Bonnier, CW Thauvoy, JF Gadisseux, JL Dutrieux and P Evrard
Department of Medical Imaging, Universite Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
In a case of pediatric Whipple disease confined to the central nervous system, white matter lesions initially appeared as areas of very low signal intensity on T1-weighted MR images and as areas of hyperintensity on proton density-weighted and T2-weighted images, and showed slight peripheral enhancement on delayed contrast-enhanced T1- weighted images. On MR studies obtained 3 and 6 months after antibiotic therapy, the lesions had decreased in size and no longer enhanced. They became progressively less hypointense on T1-weighted images and less hyperintense on T2-weighted images.
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