American Journal of Neuroradiology, Vol 17, Issue 9 1687-1690, Copyright © 1996 by American Society of Neuroradiology
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Central nervous system lymphoma not detectable on single-photon emission CT with thallium 201
DC Fisher, DP Chason, D Mathews, DK Burns and JL Fleckenstein
Department of Radiology, University of Texas Southwestern Medical Center, Dallas 75235, USA.
A 33-year-old man with acquired immunodeficiency syndrome had an erosive supraglottic mass visible on CT scans of the neck; biopsy was postponed because of the patient's debilitated condition. Two weeks later, he was admitted with altered mental status; an MR image of the brain obtained at that time showed multiple bilateral mass lesions, the largest of which was 5 cm. Findings on a thallium-201 single-photon emission CT (SPECT) scan of the brain were normal. Ten days later, the patient died and autopsy showed both the neck and the brain lesions to be large-cell lymphoma. This case is counterevidence to the reported 100% sensitivity of thallium-201 brain SPECT for demonstrating lymphoma of the central nervous system.
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