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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 20:565-567 (4 1999)
© 1999 American Society of Neuroradiology

ARTICLE

Superselective Intraarterial Fibrinolysis in Central Retinal Artery Occlusion

Riccardo Padolecchia^,a, Michele Puglioli^a, Maria Cristina Ragone^a, Andrea Romani^a and Paolo Luigi Collavoli^a

^a From the Section of Neuroradiology (R.P., M.P., P.L.C.) and the Department of Neurosciences (Section of Ophthalmology) (M.C.R., A.R.), S. Chiara Hospital, Pisa University, Italy.

Summary: Intraarterial fibrinolysis was performed in three patients with acute central retinal artery occlusion using recombinant tissue plasminogen activator as a fibrinolytic agent. In two cases the ophthalmic artery was selectively catheterized, and in the other a thrombolytic drug was infused into the ophthalmic artery by way of the meningeal collaterals. All patients experienced visual improvement. Fibrinolysis can produce better results than obtained from conservative treatment. A good prognosis can be achieved if the treatment starts within the first 4 to 5 hours after occlusion.

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