American Journal of Neuroradiology 20:609-612 (4 1999)
© 1999 American Society of Neuroradiology
ARTICLE
Decreased BOLD Functional MR Activation of the Motor and Sensory Cortices Adjacent to a Glioblastoma Multiforme: Implications for Image-Guided Neurosurgery
a From the Departments of Radiology (A.I.H., W.C.L., A.J.K.) and Neurosurgery (M.S.), UMDNJ-New Jersey Medical School, Newark; and the Department of Radiology, University of Pennsylvania, Philadelphia (J.A.M.).
Summary: A patient with a glioblastoma multiforme and mild sensorimotor deficits had significantly less activation of the motor and sensory cortices on the side with the tumor than on the contralateral side on blood oxygen leveldependent (BOLD) functional MR images. This difference, which may be due to pressure effects or loss of vascular autoregulation, should be considered in preoperative planning in which BOLD functional MR imaging is used to identify eloquent cortices to be avoided during brain tumor surgery.
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