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American Journal of Neuroradiology 20:1044-1048 (6 1999)
© 1999 American Society of Neuroradiology

ARTICLE

Clinical Use of Diffusion-Tensor Imaging for Diseases Causing Neuronal and Axonal Damage

Aziz M. Ulug,a, David F. Moorea, Aviva S. Bojkoa and Robert D. Zimmermana

a From the Departments of Radiology (A.M.U., R.Z.) and Neurology (D.F.M., A.S.B.), Cornell University Medical College-New York Presbyterian Hospital, New York.

Summary: Diffusion-tensor imaging is an emerging technique that can supply microscopic structural information about tissue in vivo. With this technique it is possible to measure the amount of anisotropy of water diffusion within tissues and to assess the degree to which directionally ordered tissues have lost their normal integrity. This study was performed in four patients to evaluate the feasibility of applying this technique in clinical situations in which there is known or suspected damage to white matter tracts.




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