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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 20:1054-1058 (6 1999)
© 1999 American Society of Neuroradiology

ARTICLE

Triple-Technique (MR Imaging, Single-Photon Emission CT, and CT) Coregistration for Image-Guided Surgical Evaluation of Patients with Intractable Epilepsy

R. Edward Hogan^,a, Val J. Lowe^a and Richard D. Bucholz^a

^a From the Department of Neurology (R.E.H.) and the Divisions of Nuclear Medicine (V.J.L.) and Neurosurgery (R.D.B.), Saint Louis University.

Summary: Ictal and interictal single-photon emission CT (SPECT) play an increasingly important role in the surgical evaluation of patients with epilepsy. We present a method of coregistration of MR, SPECT, and CT images to correlate structural data (MR imaging), blood flow changes (SPECT), and location of subdural electrodes (CT) for patients undergoing image-guided surgical treatment of epilepsy. MR-SPECT root mean square (rms) mismatch distances were 2.1 to 2.5 mm, and MR-CT rms mismatch distances were 1.0 to 4.5 mm. Coregistration assisted in image-guided placement of subdural electrodes and in surgical resection of the suspected epileptogenic focus.

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