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American Journal of Neuroradiology 21:99-104 (1 2000)
© 2000 American Society of Neuroradiology

ARTICLE

Brain Fluorine-18 Fluorodeoxyglucose Imaging with Dual-Head Coincidence Gamma Camera:Comparison with Dedicated Ring-Detector PositronEmission Tomography

Kazuki Fukuchia, Kohei Hayashida,a, Hiroshi Moriwakia, Kazuhito Fukushimaa, Norihiko Kumea, Tetsuro Katafuchia, Masayoshi Sagoa, Makoto Takamiyaa and Yoshio Ishidaa

a From the Departments of Radiology (K.Fukuc., K.H., K.Fukus., N.K., T.K., M.S., M.T., Y.I.) and Internal Medicine (H.M.), National Cardiovascular Center, Osaka, Japan.

BACKGROUND AND PURPOSE: Dual-head coincidence gamma camera (DHC) imaging has been proposed as an alternative to dedicated ring-detector positron emission tomography (dr-PET) for clinical fluorodeoxyglucose (FDG) studies. The purpose of this investigation was to assess the quality of DHC images in FDG studies of the human brain.

METHODS: Seven healthy volunteers and 12 patients with various cerebral disorders underwent consecutive brain dr-PET and DHC with FDG. All sets of images were compared semiquantitatively using regions of interest.

RESULTS: Cortical count ratios to the cerebellum on DHC and dr-PET images did not differ significantly among the volunteers, except in the superior frontal cortex and thalamus. In all studies including those of cerebral disorders, the mean cortical-to-cerebellar ratios of DHC and dr-PET images correlated closely.

CONCLUSION: FDG imaging with DHC delineated the metabolic distribution of glucose in the brain as well as dr-PET did, except in the superior frontal cortex and thalamus. Therefore, DHC may be a dedicated cost-effective means of detecting metabolic abnormalities in the brain.






Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X