AJDRAJNR - American Journal of Neuroradiology

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Case Report
BRAIN

Early Uncoupling of Cerebral Blood Flow and Metabolism after Bilateral Thalamic Infarction

Beau M. Ancesa, David S. Liebeskinda,b, Andrew B. Newbergb, Dina A. Jacobsa and Abass Alavib

a Department of Neurology, University of Pennsylvania, Philadelphia, PA
b Department of Radiology, University of Pennsylvania, Philadelphia, PA

Address correspondence to David S. Liebeskind, MD, UCLA Stroke Center and Department of Neurology, 710 Westwood Plaza, Los Angeles, CA 90095

Summary: Cerebral blood flow and metabolism may be uncoupled in the early phases after stroke onset. Prior reports of bilateral thalamic stroke have described subsequent coupling of blood flow and metabolism during the chronic stage. We chronicled the evolving relationship of blood flow and metabolism with concomitant single photon emission CT and positron emission tomography from the subacute to chronic phase following bilateral thalamic infarction.