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AJNR - American Journal of Neuroradiology

Published ahead of print on April 22, 2009
doi: 10.3174/ajnr.A1542

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American Journal of Neuroradiology 30:1685-1687, October 2009
© 2009 American Society of Neuroradiology

INTERVENTIONAL

Neck Injury Is Critical to Elastase-Induced Aneurysm Model

K. Wang^a, Q. Huang^a, B. Hong^a, Y. Xu^a, W. Zhao^a, J. Chen^a, R. Zhao^a and J. Liu^a

^aFrom the Department of Neurosurgery, Changhai Hospital of Second Military Medical University, Shanghai, P.R. China.

Please address correspondence to Jianmin Liu, MD, Department of Neurosurgery, Changhai Hospital of Second Military Medical University, Changhai Rd 168, Shanghai 200433, P.R. China; e-mail: liujm8{at}163.com

SUMMARY: We modified the elastase-induced aneurysm model by use of a simple surgical technique in rabbits. A temporary arcuated aneurysm clip was placed at the origin of the right common carotid artery (RCCA), ascertaining the inner edge of the clip blade on the juncture of the RCCA and right subclavian artery (RSCA), and the elastase-induced aneurysm procedure was undertaken. We found elastase and location of the temporary arcuated aneurysm clip are critical to the success of this aneurysm model.