AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology
DOI 10.3174/ajnr.A1158

SPINE

Brown-Séquard Syndrome Secondary to Spontaneous Bleed from Postradiation Cavernous Angiomas

M.S. Mathews, W.W. Peck and M. Brant-Zawadzki

From the Department of Neurological Surgery (M.S.M.), University of California Irvine, Irvine, Calif; and Department of Radiology (W.W.P., M.B.-Z.), Hoag Memorial Presbytarian Hospital, Newport Beach, Calif.

Please address correspondence to Marlon S. Mathews, MD, 101 The City Drive South, Bldg 56, Suite 400, Orange, CA 92898; e-mail: mmathews{at}uci.edu

SUMMARY: The spontaneous occurrence of acute Brown-Séquard syndrome is an extremely rare event, with most reported cases being secondary to spontaneous epidural hematomas and spinal cord ischemia. We report a rare case of Brown-Séquard syndrome from spontaneous intraspinal hemorrhage in a patient with multiple cavernous angiomas in the spinal cord secondary to craniospinal radiation in childhood. Postulated mechanisms leading to the condition include postradiation molecular changes and venous occlusion.






Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X