AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on February 13, 2008
doi: 10.3174/ajnr.A1029

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Magnetoencephalography for Pediatric Epilepsy: How We Do It

E.S. Schwartza, D.J. Dlugosb, P.B. Stormc, J. Della, R. Mageea, T.P. Flynnd, D.M. Zarnowa, R.A. Zimmermana and T.P.L. Robertsa

a Divisions of Neuroradiology, The Children's Hospital of Philadelphia, Philadelphia, Pa
b Neurology, The Children's Hospital of Philadelphia, Philadelphia, Pa
c Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, Pa
d Department of Psychology, The Children's Hospital of Philadelphia, Philadelphia, Pa


Figure 1
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Fig 1. A, Biomagnetometer in an electrically shielded room. Patients can be comfortably studied in a seated or supine position. B, The video screen is easily viewed and headphones facilitate communication with the technologists and allow auditory stimulus delivery. The wires attached to the 3 electrically active fiducial coils are visible.


Figure 2
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Fig 2. MEG SAMg2 data superimposed on coronal reformation (A), sagittal reformation (B), and axial MPRAGE MR imaging (C). Note the value of the t statistic indicated at the point of peak activity in the region. The statistical map overlay is thresholded to display only pixels with a t statistic value exceeding 2.0.


Figure 3
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Fig 3. Multifocal Activity. MEG interictal activity is seen as regions of color superimposed over the midportion of the superior temporal gyri bilaterally and the posterior temporal-occipital lobe junctions bilaterally on coronal reformation (A and B) and axial (C and D) MPRAGE MR images.